Modric tried to quit Spurs for Chelsea a year ago under the then management of Harry Redknapp, and this summer appears keen on a switch to Spanish champions Real Madrid.
Reports have suggested that the Croatia international has failed to travel with Spurs on the tour of America - something Villas-Boas has eluded to in the Spanish press on Sunday.
Speaking to AS, he is reported as saying: "I think Modric is wrong. This will go against him. He has worsened the situation with what he's doing and now the chairman (Daniel Levy) is very angry.
"This is also not a good time for Daniel Levy, who is in the USA at the moment, because his wife is ill."
Villas-Boas also admitted Modric would be a major loss if he leaves Spurs.
"He's good, very good. I tried to sign him last summer for Chelsea. He will be a big loss. He's a player who can make the difference, who gives a lot of clarity to the play when the team needs it and who can play in several positions," he said.
The push for more color on their cleats, adidas has added the infrared colorway to the adiZero f50 Line.
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adidas has added some color to the Predator line with this new colorway. Released on May 17. Be the first to own a pair.
The new PUMA evoSPEED 1.2 FG. A great new soccer cleat with classic look and first time for PUMA to be on the cleat.
The adidas Nitrocharge is the most talked about new cleat in years. It was released on May 15 and will take your pitch by storm.