The Stoke frontman will line-up ahead of a three-man midfield of Keith Andrews, James McCarthy and Keith Fahey with Aiden McGeady and Simon Cox providing the width with Keane missing with an Achilles injury.
Seamus Coleman has got the nod at right-back with John O'Shea, who will captain the side in Keane's absence, moving inside to partner Darren O'Dea and Stephen Ward starting on the left.
Republic team: Westwood; Coleman, O'Shea, O'Dea, Ward; McGeady, Andrews, McCarthy, Fahey, Cox; Walters.
The push for more color on their cleats, adidas has added the infrared colorway to the adiZero f50 Line.
The new PUMA evoSPEED 1.2 FG. A great new soccer cleat with classic look and first time for PUMA to be on the cleat.
adidas has added some color to the Predator line with this new colorway. Released on May 17. Be the first to own a pair.
Bayern Munich are kings of Germany and hope to be crowned kings of Europe at Wembley later this month!
Borussia Dortmund hears Wembley Calling and are headed to London for the Champions League final.
The Liverpool 2013/14 soccer jersey is available for pre-order. The Reds are eager to compete for silver next season.
One of the top soccer cleats for control the Nike CTR360 will not let you down on the field in tight spaces.
The Juventus jersey for the 2013/14 was released earlier this week. Be the first to wear the colors of the Old Lady.
Ajax has released their away soccer jersey for the 2013/14 season. Get in the Gear.
Chelsea won the Europa League on Wednesday. The Blues defeated Benfica 2-1 on injury time goal from Ivanovic.