Riki had given the visitors a shock lead on 15 minutes but Real were level seven minutes later when Ronaldo scored from the penalty spot after Manuel Pablo had brought down Angel Di Maria.
And the hosts were in cruise control by half-time as Di Maria and Ronaldo nodded in from close range just before the break.
Pepe headed in the fourth 25 minutes from time following Xabi Alonso's free-kick, before Ronaldo completed his hat-trick with another penalty after Evaldo had been harshly adjudged to have handled Kaka's cross.
Two goals in the opening 20 minutes were enough to hand Granada their first victory of the season as they withstood a second-half onslaught from Celta Vigo to win at Nuevo Los Carmenes.
Guilherme Siqueira had given the home side the lead from the penalty spot after 11 minutes and the Brazilian left-back then brilliantly set up Gabriel Torje to double the advantage moments later.
Iago Aspas quickly reduced the arrears for Celta and the hosts were thankful to goalkeeper Tono as he made a number of fine saves after the break, most notably to deny Park Chu-young an equaliser two minutes from time.
Four second-half goals - three in the last eight minutes - saw Osasuna wrap up their first victory of the season as they despatched a poor Levante side.
Emiliano Armenteros opened the scoring 10 minutes after the break before Roland Lamah (82), a David Timor penalty a minute from time and Nino's injury-time strike wrapped up a resounding victory of which there had been little indication after a poor first half.
The Nike Hypervenom is the latest cleat silo from Nike. It will change your game and is worn by the game's top players.
Germany is one of the top teams ever and they will play the US on Sunday.
Neymar's move from Santos to Barcelona is no doubt the biggest summer transfer.
Barcelona will wear this new home soccer jersey next season. They also have a new away jersey. Get them both.
Jamaica is in need of a win against the U.S. Get the jersey of the Reggae Boyz.
Support the USA national team with an official 2013 Centennial soccer jersey from Nike. Its Official.
The USA will wear their blue away jersey against Jamaica in their World Cup qualifier on Friday night.
The hoop soccer jersey is classic and cool. The USA hooped jersey is perfect for every fan. Get in the Gear.
Manchester City will try and win back the Premier League title with this new soccer jersey from Nike!
The adidas Nitrocharge is the most talked about new cleat in years. It was released on May 15 and will take your pitch by storm.