The Duke and Duchess of Cambridge will perform the official opening on Tuesday, October 9.
The Royal Party will visit the site at Burton and join specially invited guests as SGP, which was completed in July, and will eventually play host to all 24 representative England teams.
They will then meet England manager Roy Hodgson and his squad as they begin preparations for the World Cup qualifier against San Marino at Wembley on October 12.
Hope Powell, England women's senior team manager, will be joined by a number of her squad who will also meet The Duke - Honorary President of the FA - and the Duchess as they tour the facility.
FA Chairman David Bernstein said: "The opening of St. George's Park is truly a momentous occasion in the history of The FA. Next year we will celebrate The FA's 150th anniversary, and this moment will be recorded as significant as any that has gone before us in the last 149 years.
"We are particularly delighted that both the Duke and Duchess can join us to open this facility."
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