The Manchester United striker endured an afternoon to forget against the Cottagers as he started on the game on the bench and failed to finish it after being introduced as a second half substitute.
Rooney's cameo appearance was brought to an abrupt halt in stoppage time after he was caught by Fulham striker Hugo Rodallega.
The Colombia striker landed on Rooney studs first after the United frontman attempted to block a wayward shot.
A nasty cut forced the England international from the field on a stretcher and led Sir Alex Ferguson to concede afterwards that he was likely to be sidelined for up to a month.
Rooney has refused to speculate on the length of his enforced absence, but took to Twitter on Tuesday to reassure United supporters that the injury is not as bad as it looked.
"Gutted to be out for a while but my leg will be ok which is the main thing," he posted on his personal account.
The USA will wear their blue away jersey against Jamaica in their World Cup qualifier on Friday night.
Germany is one of the top teams ever and they will play the US on Sunday.
Support the USA national team with an official 2013 Centennial soccer jersey from Nike. Its Official.
The adidas Nitrocharge is the most talked about new cleat in years. It was released on May 15 and will take your pitch by storm.
The Nike Hypervenom is the latest cleat silo from Nike. It will change your game and is worn by the game's top players.
Jamaica is in need of a win against the U.S. Get the jersey of the Reggae Boyz.
Neymar's move from Santos to Barcelona is no doubt the biggest summer transfer.
Manchester City will try and win back the Premier League title with this new soccer jersey from Nike!
The hoop soccer jersey is classic and cool. The USA hooped jersey is perfect for every fan. Get in the Gear.
Barcelona will wear this new home soccer jersey next season. They also have a new away jersey. Get them both.