Deane Smalley was the hero for Oxford, scoring twice in the space of four first-half minutes in a 2-1 win against Plymouth Argyle, with Robbie Williams scoring their consolation.
Gillingham were winners by the same scoreline at Dagenham, with veteran Deon Burton setting them on their way after half an hour.
Dwight Gayle quickly equalised from the spot, but Myles Weston won it in the second half.
The other side to have been 100% before today, Accrington, were beaten 3-0 at home by Exeter.
Scottish striker Alan Gow scored twice for the Grecians, who could also afford to miss a penalty through Guillem Bauza, who then wrapped things up.
Bradford produced one of the performances of the day, beating AFC Wimbledon 5-1 at Valley Parade.
Nahki Wells scored after just three minutes, with further strikes following from Andrew Davies, Rory McArdle and James Hanson, while Curtis Haynes-Brown put through his own net as all five goals arrived in the first half.
Wimbledon's goal came before the break too, with Louis Harris netting it.
The experienced Shaun Harrad scored the only goal as Cheltenham won 1-0 at Aldershot, while York picked up their first three-point haul back in the league, as they beat Barnet 3-1.
Again all the goals were scored before the interval, with Daniel Parslow, Ashley Chambers and Michael Coulson doing the damage for City. Jon Nurse responded for Barnet.
Southend picked up their first point after securing a last-minute, 3-3 draw at Northampton.
Ryan Cresswell was their hero, but they had twice squandered the lead before that.
Britt Assombalonga's goal was cancelled out by Adebayo Akinfenwa, while Kane Ferdinand's strike was overturned by David Artell and then Alex Nicholls.
Dean Howell was on target as Fleetwood won 1-0 at Burton, while Kayode Odejayi earned Rotherham a 1-1 draw at Chesterfield, after the home side had gone in front through Jordan Bowery.
Two goals in the last two minutes from John McCombe and Tom Pope helped Port Vale win 3-1 at Morecambe, with Sam Morsy and Kevin Ellison having traded earlier efforts.
There were six goals at Plainmoor as Torquay beat Rochdale 4-2, with Andrew Tutte putting the visitors ahead before Billy Bodin, Aaron Downes and Rene Howe (two) spun it around to 4-1.
Downes was then sent off for giving away a penalty - which Jason Kennedy missed - before Ray Putterill grabbed a consolation.
Finally, Wycombe were saved by the weather as their clash with Bristol Rovers was abandoned with the Pirates 3-1 in front.
Rain fell at Adams Park with 62 minutes gone, with Lee Brown's goal and Eliot Richards' brace having put Rovers in command.
Richard Logan scored for the home side.
Chelsea won the Europa League on Wednesday. The Blues defeated Benfica 2-1 on injury time goal from Ivanovic.
Ajax has released their away soccer jersey for the 2013/14 season. Get in the Gear.
The Juventus jersey for the 2013/14 was released earlier this week. Be the first to wear the colors of the Old Lady.
The new PUMA evoSPEED 1.2 FG. A great new soccer cleat with classic look and first time for PUMA to be on the cleat.
adidas has added some color to the Predator line with this new colorway. Released on May 17. Be the first to own a pair.
One of the top soccer cleats for control the Nike CTR360 will not let you down on the field in tight spaces.
The Liverpool 2013/14 soccer jersey is available for pre-order. The Reds are eager to compete for silver next season.
Borussia Dortmund hears Wembley Calling and are headed to London for the Champions League final.
The adidas Nitrocharge is the most talked about new cleat in years. It was released on May 15 and will take your pitch by storm.
Bayern Munich are kings of Germany and hope to be crowned kings of Europe at Wembley later this month!