City will welcome their arch-rivals to the Etihad Stadium still revelling in their 6-1 league triumph at Old Trafford in October.
The tie was one of only two all-Premier League affairs to emerge from Sunday afternoon's draw, with Newcastle hosting Blackburn in the other.
The draw for the third round of the FA Cup is as follows:
Middlesbrough v Shrewsbury
Nottingham Forest v Leicester
Manchester City v Manchester United
Dagenham & Redbridge/Walsall v Millwall
Crawley v Bristol City
Doncaster v Sutton United/Notts County
Bristol Rovers v Aston Villa
Tottenham v Cheltenham
Sheffield Wednesday v West Ham
MK Dons v QPR
Hull v Ipswich
Coventry v Southampton
Brighton v Wrexham
Fulham v Charlton
Birmingham v Wolves
Norwich v Burnley
Arsenal v Leeds
Derby v Crystal Palace
Fleetwood/Yeovil v Blackpool
Swindon v Wigan
Barnsley v Swansea
Chelmsford/Macclesfield v Bolton
Newcastle v Blackburn
Everton v Tamworth
Sheffield United v Salisbury/Grimsby
Liverpool v Southend/Oldham
Gillingham v Stoke
Chelsea v Portsmouth
Watford v Bradford
Peterborough v Sunderland
West Brom v Cardiff
Reading v Stevenage
The adidas Nitrocharge is the most talked about new cleat in years. It was released on May 15 and will take your pitch by storm.
Support the USA national team with an official 2013 Centennial soccer jersey from Nike. Its Official.
The USA will wear their blue away jersey against Jamaica in their World Cup qualifier on Friday night.
Neymar's move from Santos to Barcelona is no doubt the biggest summer transfer.
Manchester City will try and win back the Premier League title with this new soccer jersey from Nike!
The Nike Hypervenom is the latest cleat silo from Nike. It will change your game and is worn by the game's top players.
Barcelona will wear this new home soccer jersey next season. They also have a new away jersey. Get them both.
England will debut their new away jersey against Brazil at the Maracana Stadium on Sunday. Get in the Gear
Germany is one of the top teams ever and they will play the US on Sunday.
The hoop soccer jersey is classic and cool. The USA hooped jersey is perfect for every fan. Get in the Gear.